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VanBavel E, Spaan JA. Branching patterns in the porcine coronary arterial tree. Estimation of flow heterogeneity Circ Res. 1992 Nov;71(5):1200-12 Hacking WJ, VanBavel E, Spaan JA. Shear stress is not sufficient to control growth of vascular networks: a model study. Spaan JA, Cornelissen AJ, Chan C, Dankelman J, Yin FC. Dynamics of flow, resistance, and intramural vascular volume in canine coronary circulation. Am J Physiol Heart Circ Physiol. 2000 Feb;278(2):H383-403. Cornelissen AJ, Dankelman J, VanBavel E, Stassen HG, Spaan JA. Myogenic reactivity and resistance distribution in the coronary arterial tree: a model study. Am J Physiol Heart Circ Physiol. 2000 May;278(5):H1490-9. Merkus D, Vergroesen I, Hiramatsu O, Tachibana H, Nakamoto H, Toyota E, Goto, M, Ogasawara Y, Spaan JA, Kajiya F. Stenosis differentially affects subendocardial and subepicardial arterioles in vivo. Cornelissen AJ, Spaan JA, Dankelman J, Chan CC, Yin FC. Evidence for stretch-induced resistance increase of proximal coronary microcirculation. Am J Physiol Heart Circ Physiol. 2001 Dec;281(6):H2687-96. Cornelissen AJ, Dankelman J, VanBavel E, Spaan JA. Am J Physiol Heart Circ Physiol. 2002 Jun;282(6):H2224-37. |
Dr E. Van Bavel (Associate Professor of Medical Physics)
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Vanbavel E, Wesselman JP and Spaan JA. Myogenic activation and calcium sensitivity of cannulated rat mesenteric small arteries. Circ Res 82: 210-220, 1998. Vanbavel E, Sorop O, Andreasen D, Pfaffendorf M and Jensen BL. Role of T-type calcium channels in myogenic tone of skeletal muscle resistance arteries. Am J Physiol Heart Circ Physiol 283: H2239-H2243, 2002. Bakker EN, van der Meulen ET, van den Berg BM, Everts V, Spaan JA and Vanbavel E. Inward remodeling follows chronic vasoconstriction in isolated resistance arteries. J Vasc Res 39: 12-20, 2002. Vanwijk MJ, Boer K, van der Meulen ET, Bleker OP, Spaan JA and Vanbavel E. Resistance artery smooth muscle function in pregnancy and preeclampsia. Am J Obstet Gynecol 186: 148-154, 2002. Sorop O, Spaan JA, Sweeney TE and Vanbavel E. Effect of steady versus oscillating flow on porcine coronary arterioles: involvement of NO and superoxide anion. Circ Res 92: 1344-1351, 2003. Bakker EN, Versluis JP, Sipkema P, VanTeeffelen JW, Rolf TM, Spaan JA and Vanbavel E. Differential structural adaptation to haemodynamics along single rat cremaster arterioles. J Physiol 548: 549-555, 2003. Vanbavel E, Siersma P and Spaan JA. Elasticity of passive blood vessels: a new concept. Am J Physiol Heart Circ Physiol 285: H1986-H2000, 2003 |
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Herrington DM, Siebes M, Sokol DK, Hsu C, Walford GD: Variability in measures of coronary luminal dimensions using quantitative coronary angiography. J Am Coll Cardiol 22: 1068-1074, 1993 Sonka M, Zhang X, Siebes M, Bissing M, DeJong SC, Collins SM, McKay CR.: Segmentation of intravascular ultrasound images: A knowledge-based approach. IEEE Trans Med Imaging 14:719-732, 1995 Siebes M, D'Argenio DZ, Campbell CS: Fluid dynamics of a partially collapsible stenosis in a flow model of the coronary circulation. J Biomech Eng 118: 489-497, 1996 Meuwissen M, Siebes M, Chamuleau SAJ, van Eck-Smit BLF, Koch KT, Tijssen JGP, Spaan JAE, Piek JJ: Hyperemic stenosis resistance index for evaluation of functional coronary lesion severity. Circulation 106:441-446, 2002 Siebes M, Chamuleau SAJ, Meuwissen M, Piek JJ, Spaan JAE: Influence of changes in hemodynamic conditions on fractional flow reserve: parametric analysis of the underlying model. Am J Physiol Heart Circ Physiol 283:H1462-H1470, 2002 Siebes M, Verhoeff B, Meuwissen M, de Winter RJ, Spaan JAE, Piek JJ: Single-wire pressure and flow velocity measurement to quantify coronary stenosis hemodynamics and effects of percutaneous interventions. Circulation 109:756-762, 2004 Verhoeff B, Siebes M, Meuwissen M, Atasever B, Voskuil M, de Winter RJ, Koch KT, Spaan JAE, Piek JJ: Influence of percutaneous coronary intervention on coronary microvascular resistance index. Circulation 111:76-82, 2005 Spaan JAE, Piek JJ, Hoffman JIE, Siebes M. Physiological basis of clinically used coronary hemodynamic indices [Basic Science for Clinicians]. Circulation 113:446-455, 2006 Verberne HJ, Meuwissen M, Chamuleau SAJ, Verhoeff BJ, van Eck-Smit BLF, Spaan JAE, Piek JJ, Siebes, M. Effect of simultaneous intracoronary guide wires on the predictive accuracy of functional parameters of coronary lesion severity. Am J Physiol Heart Circ Physiol, 292:H2349-H2355, 2007 Siebes M, Viceconti M, Maglaveras N, Kirkpatrick J. Engineering for Health: A partner in building the knowledge economy of Europe Eng Med Biol Mag26:53-59, 2007 (Special Edition on BME Trends in Europe)
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Key Publications 'Medical Imaging'
· Venema, H.W., F.J.H. Hulsmans, G.J. den Heeten. CT angiography of the circle of Willis and intracranial internal carotid arteries: Maximum intensity projection with matched mask bone elimination - Feasibility study. Radiology 218, 893-898, 2001.
· Snel, J.G., H.W. Venema, T.M. Moojen, M.J.P.F.Ritt, C.A. Grimbergen, G.J. den Heeten. Quantitative in vivo analysis of the kinematics of carpal bones from three-dimensional CT images using a deformable surface model and a three-dimensional matching technique. Med. Phys. 27, 2037-2047, 2000.
· Venema, H.W., S.S. Phoa, P.G. Mirck, F.J. Hulsmans, C.B. Majoie, B. Verbeeten Jr. Petrosal bone: coronal reconstructions from axial spiral CT data obtained with 0.5-mm collimation can replace direct coronal sequential CT scans. Radiology 213, 375-82, 1999.
· G.J. Streekstra, R. van den Boomgaard, A.W.M. Smeulders. Scale dependency of image derivatives for feature measurement in curvilinear structures. International Journal of Computer Vision 42(3), 177-189, 2001.
· Snel, J.G., H. Venema, C.A. Grimbergen. Detection of the Carpal Bone contours from 3-D- MR Images of the wrist. IEEE Transactions on Medical Imaging 17, 1063-1072, 1998.
· Jonges R., P.N.M. Boon, J. Van Marle, A.J.J. Dietrich, C.A. Grimbergen. CART: a controlled algebraic reconstruction technique for electron microscope tomography of embedded, sectioned specimen. Ultramicroscopy 77, 203-219, 1999.
Key Publications 'Minimally Invasive Surgery and Interventional Techniques'
· Grimbergen, C.A. Minimal Invasive Surgery: Human-Machine Aspects and Engineering Approaches. In: Perspectives on the human controller, Eds T.B. Sheridan and T. van Lunteren , 1997.
· Stassen, H.G., J. Dankelman, C.A. Grimbergen. Open versus minimally invasive surgery - A man-machine system approach. Trans. Inst. MC. 21, 151-162, 1999.
· Claus G.P., W. Sjoerdsma, A. Jansen, C.A. Grimbergen. Quantitative standardised analysis of advanced laparoscopic surgical procedures. Endoscopic Surgery and Allied Technologies 4(3), 209-213, 1995.
· Sjoerdsma, W., J.L. Herder, M.J. Horward, A. Jansen, J.J.G. Bannenberg, C.A. Grimbergen. Force transmission of laparoscopic grasping instruments. Minimally Invasive Therapy and Allied Technology 6(4), 274-278, 1997.
· Jaspers J.E.N., K.T. den Boer, W. Sjoerdsma, M. Bruijn, C.A. Grimbergen. Design and feasibility of PASSIST, a passive instrument positioner. Journal of Laparoendoscopic & Advanced Surgical Techniques-Part A 10(6), 331-335, 2000.
· Sjoerdsma W., D.W. Meijer, A. Jansen, K.T. den Boer, C.A. Grimbergen. Comparison of efficiencies of three techniques for colon surgery. Journal of Laparoendoscopic & Advanced Surgical Techniques-Part A 10(1), 47-53, 2000.
Key Publications 'Implications of the Endothelial Cell Glycocalyx for Vascular Function'
· Constantinescu A.A., H. Vink, J.A.E. Spaan. Elevated capillary tube hematocrit reflects degradation of the endothelial cell glycocalyx by oxidized LDL. Am. J. Physiol. 280, H1051-H1057, 2001.
· Vink, H., A.A. Constantinescu, J.A.E. Spaan. Oxidized lipoproteins degrade the endothelial cell surface layer: Implications for platelet-endothelial cell adhesion. Circulation 101(13), 1500-1502, 2000.
· Vink, H., and B.R. Duling. Capillary endothelial surface layer selectively reduces plasma solute distribution volume. Am. J. Physiol. 278, H285-H289, 2000.
· Vink, H., and B.R. Duling. Identification of distinct luminal domains for acromolecules, erythrocytes and leukocytes within mammalian capillaries. Circulation Research 79, 581-589, 1996.
Key Publications Structure and Function of Small Blood Vessels
· Bakker, E.P., E.T. Van der Meulen, J.A.E. Spaan, E. VanBavel. Organoid culture of cannulated rat resistance arteries: effect of serum factors on vasoactivity and remodeling. Am. J. Physiol. 278, H1233-H1240, 2000.
· Goto, M., E. VanBavel, M.J.M.M. Giezeman, J.A.E. Spaan. Vasodilatory effect of pulsatile pressure on coronary resistance vessels. Circ.Res. 79, 1039-1045, 1996.
· VanBavel, E. and J.A.E. Spaan. Branching patterns in the porcine coronary arterial tree: Estimation of flow heterogeneity. Circ.Res. 71, 1200-1212, 1992.
· VanBavel, E., J.P. Wesselman, J.A. Spaan. Myogenic activation and calcium sensitivity of cannulated rat mesenteric small arteries. Circ.Res. 82, 210-220, 1998.